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Oh no. Is it syphilis?

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It could be. Here’s what you need to know.
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Syphilis happens... to be a risk for anyone who is sexually active.
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What is syphilis?

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Syphilis is a common sexually transmitted bacterial infection that spreads through unprotected sex. Sexually active people can get syphilis through vaginal, anal, or oral sex without a condom with a partner who has syphilis.

It doesn't care about your age, gender, sexuality, or how many people you’ve slept with. It’s an infection, and one you can treat.

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Anyone who has unprotected sex can get syphilis.

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That’s right—anyone who has unprotected sex can get syphilis. That's why it's so important to practice safe sex and get regular testing as needed.

Some groups are more commonly affected by syphilis, including*:

  • People between the ages of 20 and 34
  • Men
  • Men who have sex with men
  • Black men
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Some groups have shown a rise recently in syphilis*:

  • People 55+
  • Women
  • Pregnant women
    • Infants who can get it through their mothers (congenital syphilis)


Knowing your risk and taking steps to protect yourself can make a big difference.

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*Rates of reported primary and secondary syphilis cases, unless otherwise noted.
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What are the stages of syphilis?

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Syphilis comes in 4 stages, and it can look very different at each one:
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Primary stage

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What to watch for: A painless sore (called a chancre) on or near your genitals, mouth, or rectum

Why it matters: It can be tricky to spot because it often heals on its own, but the infection stays dormant in your body

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Secondary stage

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What to watch for: A skin rash, fever, sore throat, swollen glands, or hair loss

Why it matters: These symptoms mimic other illnesses. Without treatment, syphilis will continue to live in your body, progressing further

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Latent stage

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What to watch for: Syphilis will have no visible symptoms, remaining completely silent

Why it matters: You may feel fine, but syphilis is still there and causing harm to your body

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Tertiary stage (rare but dangerous)

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What to watch for: 10-30 years after the initial infection, untreated syphilis can damage your heart, brain, nerves, and possibly lead to death
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What if you’ve had syphilis before?

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You can catch syphilis again, even if you've been treated before.
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How does syphilis spread?

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Syphilis can spread through:

  • Unprotected vaginal, oral, or anal sex
  • Skin-to-skin contact with a syphilis sore
  • From mother to baby during pregnancy (called congenital syphilis)

It's important to know syphilis can spread even when there are no symptoms. That’s why regular testing is so important—not just for you and those you care about, but also for potential future partners.

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How do I protect myself?

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There are simple and effective ways to protect yourself from sexually transmitted infections like syphilis:

  • Using condoms and dental dams
  • Getting tested regularly
  • Having consistent, transparent, and open conversations with your partners and healthcare providers
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What is congenital syphilis?

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Congenital syphilis happens when syphilis is passed from a pregnant mother to her baby during pregnancy or birth. It can cause serious health problems for the baby, including premature birth, low birth weight, or even stillbirth.

The good news? Congenital syphilis is preventable. Getting tested and treated early in pregnancy can protect both you and your baby. Syphilis can be curable with the right treatments from your healthcare provider.

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Learn more about congenital syphilis
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Here are resources to help you move forward

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Links to all outside sites are provided as a resource to our visitors. Pfizer accepts no responsibility for the content of sites that are not owned and operated by Pfizer.
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Get tested

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Find a testing location
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Explore resources from the Centers for Disease Control and Prevention

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Explore syphilis resources
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Talk to your doctor

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Download our discussion guide
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All images on this website feature actors for illustrative purposes only. They do not represent real patients, providers, or clinical scenarios.